货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
T25569-1mg	98%	￥11200.00 T25569-1mg ￥11200.00 2-4周	0 货期：2-4周	-	-	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

T25569-1mg

98%

￥11200.00

货期：2-4周

靶点：

Benzodiazepine receptor

体内研究：

At all times plasma levels of Ro 41-3290, the desethylated derivative of Ro 41-3696, are higher than those of the parent drug (tmax and t1/2 values=~2 and 8 hours, respectively). Pharmacokinetics of both Ro 41-3696 and its O-desethyl metabolite Ro 41-3290 are dose proportional and time independent. Ro 41-3696 is absorbed and eliminates rapidly (time of maximum plasma concentration, approximately 1 hour; elimination half-life, approximately 2 hours). Plasma levels of Ro 41-3290 are higher than those of the parent drug, and it is more slowly eliminated (values for time of maximum plasma concentration and elimination half-life, approximately 2 and approximately 7 hours, respectively).

参考文献：

1. Dingemanse J, et al. Pharmacokinetics and pharmacodynamics of Ro 41-3696, a novel nonbenzodiazepine hypnotic. J Clin Pharmacol. 1995 Aug;35(8):821-9.
2. Dingemanse J, et al. Multiple-dose tolerability, pharmacodynamics, and pharmacokinetics of the quinolizinone hypnotic Ro 41-3696 in elderly subjects. Clin Neuropharmacol. 2001 Mar-Apr;24(2):82-90.

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.376 ml	11.88 ml	23.759 ml
5 mM	0.475 ml	2.376 ml	4.752 ml
10 mM	0.238 ml	1.188 ml	2.376 ml
50 mM	0.048 ml	0.238 ml	0.475 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

Ro 41-?3290