货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
T27418-1mg	≥99%	￥1650.00 T27418-1mg ￥1650.00 2-4周	0 货期：2-4周	-	-	-	-
T27418-5mg	≥99%	￥3300.00 T27418-5mg ￥3300.00 2-4周	0 货期：2-4周	-	-	-	-

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体内研究：

YS-201 (Diperdipine) markedly reduces systemic vascular resistance and improves stroke index and left ventricular ejection fraction. Mean pulmonary artery and wedge pressures are slightly increased as a possible consequence of enhanced venous return, whereas right atrial and left ventricular end-diastolic pressures are not significantly changed. Nevertheless, an increase in preload is clearly indicated by an augmented left ventricular end-diastolic volume index after administration of diperdipine. After intravenous and oral doses, absolute bioavailability is calculated to be 18.7%. Biliaryexcretion accounts for about 0.1% of the total clearance of diperdipine and does not contribute to the overall elimination of the drug. After intraportal administration, the bioavailable fraction of diperdipine is increasing up to 44.3% suggesting a prehepatic site of loss of the drug. The single application of diperdipine to mice and rats by gavage causes intolerance reactions starting at the lowest tested dose level of 200 mg/kg b.w. p.o. (mice) and at 250 mg/kg b.w. p.o. (rats). In the rat, toxic effects occur from 15 mg diperdipine/kg b.w./day p.o. onwards.

保存条件：

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.186 ml	10.928 ml	21.857 ml
5 mM	0.437 ml	2.186 ml	4.371 ml
10 mM	0.219 ml	1.093 ml	2.186 ml
50 mM	0.044 ml	0.219 ml	0.437 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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分子摩尔量

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