Zileuton (sodiuM)

98%

Zileuton (sodiuM)

产品使用指南

品牌：源叶(MedMol)

产品编号：T27633 一键复制产品信息

CAS号：118569-21-4

分子式：C₁₁H₁₂N₂NaO₂S *

分子量：259.27995

别名：Zileuton sodium

货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
T27633-10mg	98%	￥390.00 T27633-10mg ￥390.00 2-4周	0 货期：2-4周	-	-	-	-
T27633-50mg	98%	￥1190.00 T27633-50mg ￥1190.00 2-4周	0 货期：2-4周	-	-	-	-

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产品介绍参考文献(1篇) 质检证书(COA) 摩尔浓度计算器相关产品

体内研究：

In Zileuton sodium (A 64077 sodium) (5 mg/kg, p.o.) treated I/R rat, the effect of Zileuton to decrease NF-κB expression does not change significantly in the presence of COX inhibitors, and the group reveals significantly lower level of NF-κB staining. Zileuton (5 mg/kg, p.o.) treatment given to I/R rats decreases apoptotic index significantly. Zileuton has no significant effect on increased serum TNF-α levels in I/R group.
Zileuton sodium (A 64077 sodium) (1200 mg/kg) inhibits the polyp formation in APCΔ468 colon and small intestine. Zileuton treatment inhibits the proliferation rates of non epithelial cells in polyps, and increases the apoptosis rates in polyps in rat. There is significant increase in the number of apoptotic cells in the Zileuton-treated cells both in small intestine and in the colon. The reduced proliferation rate may significantly contribute to the reduction of polyposis in both the small intestine and colon of Zileuton-fed APCΔ468 mice.

保存条件：

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.857 ml	19.284 ml	38.568 ml
5 mM	0.771 ml	3.857 ml	7.714 ml
10 mM	0.386 ml	1.928 ml	3.857 ml
50 mM	0.077 ml	0.386 ml	0.771 ml