NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
靶点:
Cleavable;PEGs
参考文献:
1. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1.