| 产品描述: | F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. F16 is a mitochondriotoxic compound, and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell |
| 靶点: |
Apoptosis |
| 参考文献: |
1. Fantin VR et al. A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth. Cancer Cell. 2002 Jul;2(1):29-42. 2. Fantin VR et al. F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell. Cancer Res. 2004 Jan 1;64(1):329-36. |
| 溶解性: |
Soluble in DMSO、Ethanol |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.761 ml |
13.804 ml |
27.608 ml |
| 5 mM |
0.552 ml |
2.761 ml |
5.522 ml |
| 10 mM |
0.276 ml |
1.38 ml |
2.761 ml |
| 50 mM |
0.055 ml |
0.276 ml |
0.552 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |