MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1)
靶点:
Malat1
参考文献:
1.Abulwerdi et al (2019) Selective small-molecule targeting of a triple helix encoded by the long noncoding RNA, MALAT1. ACS Chem.Biol. 14 223 PMID: 30620551