| 产品描述： | HA-100 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor |
| 靶点： |
PKC:12 μM (IC50);PKG:4 μM (IC50);PKA:8 μM (IC50);MLCK:240 μM (IC50);PKC:6.5 μM (Ki);MLCK:61 μM (Ki) |
| 参考文献： |
1. Hagiwara M, et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol. 1987 Jul;32(1):7-12. 2. Yu J, et, al. Efficient feeder-free episomal reprogramming with small molecules. PLoS One. 2011 Mar 1;6(3):e17557. |
| 溶解性： |
Soluble in DMSO |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.606 ml |
18.028 ml |
36.057 ml |
| 5 mM |
0.721 ml |
3.606 ml |
7.211 ml |
| 10 mM |
0.361 ml |
1.803 ml |
3.606 ml |
| 50 mM |
0.072 ml |
0.361 ml |
0.721 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京