| 产品描述： | Brassinin (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities. |
| 靶点： |
Antifungal |
| 体内研究： |
Brassinin attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3). |
| 参考文献： |
1. Kim SM,etal.Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.Phytother Res. 2014 Mar;28(3):423-31. 2. Lee JH,et al.Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel.Oncotarget. 2015 Mar 20;6(8):6386-405. 3. Pedras MS,etal.Phytoalexins from the crucifer rutabaga: structures, syntheses, biosyntheses, and antifungal activity.J Org Chem. 2004 Jun 25;69(13):4471-6. |
| 溶解性： |
Soluble in DMSO |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
4.231 ml |
21.155 ml |
42.31 ml |
| 5 mM |
0.846 ml |
4.231 ml |
8.462 ml |
| 10 mM |
0.423 ml |
2.116 ml |
4.231 ml |
| 50 mM |
0.085 ml |
0.423 ml |
0.846 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京