| 产品描述： | ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3. |
| 体外研究： |
ChX710 treatment is found to efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels . |
| 参考文献： |
1. Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7(1):2561. |
| 溶解性： |
Soluble in DMSO、H2O |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 备注： |
ChX710可以启动 I 型干扰素对胞质 DNA 的反应，诱导 ISRE 启动子序列、特异性细胞干扰素刺激基因 (ISGs) 和干扰素调节因子(IRF) 3的磷酸化。 |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.092 ml |
15.461 ml |
30.922 ml |
| 5 mM |
0.618 ml |
3.092 ml |
6.184 ml |
| 10 mM |
0.309 ml |
1.546 ml |
3.092 ml |
| 50 mM |
0.062 ml |
0.309 ml |
0.618 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京