| 产品描述： | DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons |
| 体内研究： |
DSP-4 hydrochloride (i.p.; 50 mg/kg; single) destroys the LC neurons and fibers. Animal Model: rats Dosage: 50 mg/kg Administration: intraperitoneal , single Result: Not visualized large projection neurons and the fibers of the LC. |
| 参考文献： |
1. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41. 2. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23. |
| 溶解性： |
Soluble in DMSO、H2O |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.194 ml |
15.971 ml |
31.943 ml |
| 5 mM |
0.639 ml |
3.194 ml |
6.389 ml |
| 10 mM |
0.319 ml |
1.597 ml |
3.194 ml |
| 50 mM |
0.064 ml |
0.319 ml |
0.639 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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