Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
靶点:
Cereblon
参考文献:
1. Andrew P. Crew, et al. Imide-based modulators of proteolysis and associated methods of use. US20160058872A1.