| 产品描述: | NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer. |
| 靶点: |
Apoptosis |
| 体外研究: |
NSC 146109 hydrochloride promotes breast cancer cells to undergo apoptosis through activating p53 and inducing the expression of proapoptotic genes |
| 参考文献: |
1. Wang H, et al. A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells. Neoplasia. 2011 Jul;13(7):611-9. |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.156 ml |
15.78 ml |
31.561 ml |
| 5 mM |
0.631 ml |
3.156 ml |
6.312 ml |
| 10 mM |
0.316 ml |
1.578 ml |
3.156 ml |
| 50 mM |
0.063 ml |
0.316 ml |
0.631 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |