| 产品描述: | CTX-0294885 is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. CTX-0294885 is a powerful reagent for analysis of kinome signaling networks that can be used for the research of diseases like inflammation, diabetes, and cancer |
| 靶点: |
Akt |
| 体外研究: |
CTX-0294885 is a kinase capture tool in large-scale kinome profiling experiments, with 185 kinases identified as total protein, and 179 identified from TiO2 enrichment for phosphopeptides in MDA-MB-231 cells (by quantitative MS). CTX-0294885 captures all members of the AKT family that is not identified from previous studies using other kinase capture reagents |
| 参考文献: |
1. Zhang L, et al. Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling. J Proteome Res. 2013 Jul 5;12(7):3104-16. |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.283 ml |
11.417 ml |
22.835 ml |
| 5 mM |
0.457 ml |
2.283 ml |
4.567 ml |
| 10 mM |
0.228 ml |
1.142 ml |
2.283 ml |
| 50 mM |
0.046 ml |
0.228 ml |
0.457 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |