| 产品描述: | CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation |
| 靶点: |
NPBWR1, GPR7 |
| 体外研究: |
CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner Cell Proliferation Assay Cell Line: ATDC5 (exposed with 200 ng/mL NPW-23 for 24 h) Concentration: 1 and 3 μM Incubation Time: 30 min Result: Attenuated the NPW-23-induced cell proliferation in a dose-dependent manner. |
| 参考文献: |
1. Guerrero et al (2013) SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg.Med.Chem.Lett. 23 614 PMID: 23287738 |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.399 ml |
11.995 ml |
23.989 ml |
| 5 mM |
0.48 ml |
2.399 ml |
4.798 ml |
| 10 mM |
0.24 ml |
1.199 ml |
2.399 ml |
| 50 mM |
0.048 ml |
0.24 ml |
0.48 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |