| 产品描述： | TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 |
| 靶点： |
PAR1 |
| 体内研究： |
TRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats |
| 参考文献： |
1. Kahn ML, et, al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999 Mar;103(6):879-87. 2. Kinlough-Rathbone RL, et, al. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood. 1993 Jul 1;82(1):103-6. 3. Chintala MS, et, al. Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats. Eur J Pharmacol. 1998 May 22;349(2-3):237-43. |
| 溶解性： |
H2O : 25 mg/mL (33.38 mM; Need ultrasonic) |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.335 ml |
6.677 ml |
13.353 ml |
| 5 mM |
0.267 ml |
1.335 ml |
2.671 ml |
| 10 mM |
0.134 ml |
0.668 ml |
1.335 ml |
| 50 mM |
0.027 ml |
0.134 ml |
0.267 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京