| 产品描述: | C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages |
| 靶点: |
Bacterial |
| 参考文献: |
1. Stanley SA, Grant SS, Kawate T, et al. Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening. ACS Chem Biol. 2012;7(8):1377-1384. |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.663 ml |
13.316 ml |
26.631 ml |
| 5 mM |
0.533 ml |
2.663 ml |
5.326 ml |
| 10 mM |
0.266 ml |
1.332 ml |
2.663 ml |
| 50 mM |
0.053 ml |
0.266 ml |
0.533 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |