| 产品描述: | ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity |
| 靶点: |
SARS-CoVVirus Protease |
| 参考文献: |
1. Jacobs J, et al. Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus |
| 溶解性: |
Soluble in DMSO |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.307 ml |
11.533 ml |
23.066 ml |
| 5 mM |
0.461 ml |
2.307 ml |
4.613 ml |
| 10 mM |
0.231 ml |
1.153 ml |
2.307 ml |
| 50 mM |
0.046 ml |
0.231 ml |
0.461 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |