货号	规格	价格	上海	北京	珠海	重庆	武汉
T31221-5mg买3赠1	99.60%	￥240.00 T31221-5mg ￥240.00 现货（买3赠1）	2 2	-	-	-	-
T31221-10mg买3赠1	99.60%	￥340.00 T31221-10mg ￥340.00 现货（买3赠1）	3 3	-	-	-	-
T31221-25mg买3赠1	99.60%	￥570.00 T31221-25mg ￥570.00 现货（买3赠1）	2 2	-	-	-	-
T31221-100mg买3赠1	99.60%	￥1100.00 T31221-100mg ￥1100.00 现货（买3赠1）	5 5	-	-	-	-

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产品描述：

Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions

靶点：

Human Endogenous Metabolite;EndogenousMetabolite

体外研究：

Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation。

体内研究：

Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo。

参考文献：

1. Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32.

溶解性：

Soluble in DMSO、H2O

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	5.945 ml	29.727 ml	59.453 ml
5 mM	1.189 ml	5.945 ml	11.891 ml
10 mM	0.595 ml	2.973 ml	5.945 ml
50 mM	0.119 ml	0.595 ml	1.189 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(2篇)

2. [IF=4.7] Guo-Ying Chen et al."Rapid and sensitive detection of alkaline phosphatase and glucose oxidase activity through fluorescence and colorimetric dual-mode analysis based on CuO NPs@ZIF-8 mediated enzyme-cascade reactions."Nanoscale Advances.2023 Aug;: 1. [IF=4.27] Jieren Liao et al."GABA shunt contribution to flavonoid biosynthesis and metabolism in tea plants (Camellia sinensis)."Plant Physiol Bioch. 2021 Sep;166:849

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

吡多胺

pyridoxamine

参考文献(2篇)

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)