3-脱氧葡萄糖醛 ≥95%
| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T54285-1mg促销 |
≥95% | ￥2000.00 ￥1520.00 |
货期：3-5天 | - | - | - | - |
|
T54285-5mg |
≥95% | ￥3600.00 |
货期：3-5天 | - | - | - | - |
|
T54285-10mg |
≥95% | ￥6000.00 |
货期：2-3天 | - | - | - | - |
|
| 体内研究： | 3-Deoxyglucosone (intragastric administration; 20 mg/kg; single dose) impairs glucose tolerance with increased AUC, but the plasma glucagon levels are not significantly different. It developes impaired glucose regulation (IGR) with obviously pancreatic islet cell dysfunction in kunming mice and SD-rats. 3-deoxyglucosone (gastric gavage; 5-50 mg/kg; once daily; 2 weeks) is significantly increased in the upper small intestine (1.4-fold), lower small intestine (1.4-fold), ileum (1.4-fold) and colon (two fold) compared with the basal levels in the corresponding control group. In addition, the protein expressions of TAS1R2, TAS1R3 and TRPM5 in both duodenum and colon are significantly decreased. |
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| 参考文献： | 1. Song X, et al. 3-Deoxyglucosone Induces Glucagon-Like Peptide-1 Secretion from STC-1 Cells via Upregulating Sweet Taste Receptor Expression under Basal Conditions.Int J Endocrinol. 2019 Oct 23;2019:4959646. 2. Wang F, et al. Acute Reduction of Incretin Effect and Glucose Intolerance in Rats by Single Intragastric Administration of 3-deoxyglucosone. Exp Clin Endocrinol Diabetes. 2017 Jan;125(1):4-11. 3. Zhang L, et al. Accumulation of intestinal tissue 3-deoxyglucosone attenuated GLP-1 secretion and its insulinotropic effect in rats. Diabetol Metab Syndr. 2016 Nov 29;8:78. 4. Niwa T, et al. 3-Deoxyglucosone: metabolism, analysis, biological activity, and clinical implication.J Chromatogr B Biomed Sci Appl. 1999 Aug 6;731(1):23-36. |
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| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
参考文献(3篇)
3. [IF=8.7] Ying Xu, et al. "Investigation of the three pectin fractions variation impact on the Maillard reaction in dried crabapple storage"INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2026 Jun;365:152380
2. [IF=3.3] Tan Linzhi et al."Protein deterioration and α-dicarbonyls in precooked fish during storage and reheating affected by the severity of precooking treatments."Journal of Food Measurement and Characterization.2025 May;:1-12
1. [IF=6.1] Hao Huang et al."Maillard reaction intermediates in Chinese Baijiu and their effects on Maillard reaction related flavor compounds during aging."Food Chemistry-X".2024 Jun;22:101356
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