| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T76070-1mg促销 |
98% | ￥300.00 ￥175.00 |
货期：3-5天 | - | - | - | - |
|
T76070-5mg买3赠1 |
98.00% | ￥560.00 |
5 | - | - | - | - |
|
T76070-10mg买3赠1 |
98.00% | ￥890.00 |
5 | - | - | - | - |
|
T76070-25mg买3赠1 |
98.00% | ￥1600.00 |
3 | - | - | - | - |
|
T76070-100mg |
98% | ￥5600.00 |
货期：2-3天 | - | - | - | - |
|
| 产品描述： | MG115 is an inhibitor of NFκB in the cytoplasm by acting on IKK or the proteasome. |
||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | Ki: 21 nM (20S proteasome); 35 nM (26 Sproteasome) | ||||||||||||||||||||
| 参考文献： | 1. Kaźmierczak A, Doniak M, Kunikowska A. Proteolytic activities in cortex of apical parts of Vicia faba ssp. minor seedling roots during kinetin-induced programmed cell death. Protoplasma. 2017 Nov;254(6):2273-2285. doi: 10.1007/s00709-017-1119-7. Epub 2017 May 13. PubMed PMID: 28501974. 2. Kim A, Nam YJ, Lee MS, Shin YK, Sohn DS, Lee CS. Apigenin Reduces Proteasome Inhibition-Induced Neuronal Apoptosis by Suppressing the Cell Death Process. Neurochem Res. 2016 Nov;41(11):2969-2980. Epub 2016 Jul 29. PubMed PMID: 27473386. 3. Nam YJ, Kim A, Lee MS, Shin YK, Sohn DS, Lee CS. Lamotrigine Attenuates Proteasome Inhibition-Induced Apoptosis by Suppressing the Activation of the Mitochondrial Pathway and the Caspase-8- and Bid-Dependent Pathways. Neurochem Res. 2016 Oct;41(10):2503-2516. Epub 2016 May 26. PubMed PMID: 27230883. 4. Nam YJ, Lee DH, Lee MS, Lee CS. K(ATP) channel block prevents proteasome inhibitor-induced apoptosis in differentiated PC12 cells. Eur J Pharmacol. 2015 Oct 5.764:582-91. doi: 10.1016/j.ejphar.2015.06.049. Epub 2015 Jul 2. PubMed PMID: 26142827. 5: Katayama K, Kapoor K, Ohnuma S, Patel A, Swaim W, Ambudkar IS, Ambudkar SV. Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2361-70. doi: 10.1016/j.bbamcr.2015.06.001. Epub 2015 Jun 6. PubMed PMID: 26057472; PubMed Central PMCID: PMC4558211. |
||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
|
||||||||||||||||||||
| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
沪公网安备 31011702002021号
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京