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Modecainide

    
≥98%

Modecainide

源叶(MedMol)
T77059 一键复制产品信息
81329-71-7
C22H28N2O3
368.47
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T77059-1mg促销
≥98%

¥340.00 ¥306.00

9 - - - -
T77059-5mg促销
≥98%

¥998.00 ¥898.00

5 - - - -
T77059-10mg促销
≥98%

¥1520.00 ¥1370.00

3 - - - -
T77059-25mg促销
≥98%

¥2900.00 ¥2610.00

3 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
体内研究: The effect of Encainide and its two major metabolites, O-demethylated Encainide (MJ 9444) and 3-O-methoxy Encainide (MJ 14030), on cardiac conduction is studied by recording His bundle potentials in isolated perfused rabbit hearts and Purkinje and muscle conduction in vivo in dog hearts after destruction of the atrioventricular node. Both metabolites are 4 to 15 times more potent than Encainide in slowing conduction through the atria, the AV-node and the His-Purkinje system of the rabbit heart. In the dog, Encainide (0.8-3.2 mg/kg i.v.) slows conduction of extrasystoles in both Purkinje and muscle at all coupling intervals, increases the effective refractory period and the functional refractory period of the Purkinje pathway. MJ 9444 (0.05-0.4 mg/kg) speeds Purkinje conduction of early (less than 300 msec) without affecting or while slowing conduction of late (greater than 350 msec) extrasystoles. Higher doses (0.4-1.6 mg/kg) slows conduction at all intervals. The effective refractory period and the functional refractory period are decreased but in some cases returned to control values at the higher doses. Muscle conduction is slowed at doses of 0.4 mg/kg or more. MJ 14030 (0.05-3.2 mg/kg) has variable effects, behaving like MJ 9444 in three experiments but like the parent compound in two others.
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.714 ml 13.57 ml 27.139 ml
5 mM 0.543 ml 2.714 ml 5.428 ml
10 mM 0.271 ml 1.357 ml 2.714 ml
50 mM 0.054 ml 0.271 ml 0.543 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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