货号	价格	上海	北京	珠海	重庆	武汉
T79568-10mg	￥3540.00 T79568-10mg ￥3540.00 3-5天	0 货期：3-5天	-	-	-	-
T79568-25mg	￥6760.00 T79568-25mg ￥6760.00 3-5天	0 货期：3-5天	-	-	-	-
T79568-100mg	￥20000.00 T79568-100mg ￥20000.00 3-5天	0 货期：3-5天	-	-	-	-

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靶点：

non-CB1 vascular cannabinoid receptor, GPR18.

体内研究：

Decreases in HR, blood pressure, MBF and RBF by about 20 beats/min, 5-10 mmHg and 0.7 and 0.2 mL/min, respectively, are observed after injection of O1918 (3 μmol/kg). O1918 causes an inhibition of the anandamide-stimulated decreases in MBP, SBP and DBP by 55, 38 and 42% respectively. Similarly, this antagonist reduces the methanandamide-stimulated fall in SBP and DBP by 44 and 32%, respectively, and tends to diminish the decrease in MBP by 28%. O1918 also diminishes the fall in MBF and RBF induced by anandamide by 61 and 67% and that induced by methanandamide by 74 and 49% respectively. Cannabidiol does not affect basal cardiovascular parameters whereas O1918 decreases HR by about 15 beats/min and SBP, DBP and MBP by about 15 mmHg. In pithed rats anandamide (3 μmol/kg) causes only an increase in MBF and RBF. The anandamide-induced long-lasting fall in MBP, SBP and DBP is reduced by cannabidiol by 40-46% and by O-1918 by 55, 64 and 35, respectively.

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.491 ml	17.457 ml	34.915 ml
5 mM	0.698 ml	3.491 ml	6.983 ml
10 mM	0.349 ml	1.746 ml	3.491 ml
50 mM	0.07 ml	0.349 ml	0.698 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

1,3-二甲氧基-5-甲基-2-[(1R,6R)-3-甲基-6-(1-甲基乙烯基)-2-环己烯-1-基]苯

O-1918

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)