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RS 67333 盐酸盐

    
≥95%

1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[1-BUTYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE

源叶(MedMol)
T83647 一键复制产品信息
168986-60-5
C19H30Cl2N2O2
389.36
RS 67333盐酸盐;1-(4-氨基-5-氯-2-甲氧基苯基)-3-(1-丁基-4-哌啶基)-1-丙酮盐酸盐;1-(4-AMINO-5-CHLORO-2-METHOXYPHENYL)-3-[1-BUTYL-4-PIPERIDINYL]-1-PROPANONE HYDROCHLORIDE;RS 67333 HYDROCHLORIDE;RS67333HCl;1-(4-AMino-5-chloro-2;RS 67333 hydrochloride
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T83647-5mg促销
≥95%

¥842.00 ¥756.00

10 - - - -
T83647-10mg促销
≥95%

¥1640.00 ¥1480.00

10 - - - -
T83647-25mg促销
≥95%

¥2710.00 ¥2440.00

6 - - - -
T83647-50mg促销
≥95%

¥4620.00 ¥4150.00

4 - - - -
T83647-100mg促销
≥95%

¥9190.00 ¥8270.00

1 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride has neuroprotective effects, and can be used for Alzheimer's disease research
靶点: 5-HT4 Receptor:8.7 (pKi);5-HTReceptor
体外研究: RS 67333 hydrochloride does exhibit affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT.
参考文献: 1. R M Eglen, et al. Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol. 1995 Aug;115(8):1387-92.
溶解性: Soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.568 ml 12.842 ml 25.683 ml
5 mM 0.514 ml 2.568 ml 5.137 ml
10 mM 0.257 ml 1.284 ml 2.568 ml
50 mM 0.051 ml 0.257 ml 0.514 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

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