货号	规格	价格	上海	北京	珠海	重庆	武汉
T87784-5mg买3赠1	98.50%	￥680.00 T87784-5mg ￥680.00 现货（买3赠1）	5 5	-	-	-	-
T87784-10mg买3赠1	98.50%	￥1100.00 T87784-10mg ￥1100.00 现货（买3赠1）	7 7	-	-	-	-
T87784-25mg买3赠1	98.50%	￥2210.00 T87784-25mg ￥2210.00 现货（买3赠1）	5 5	-	-	-	-
T87784-100mg	≥98%	￥5390.00 T87784-100mg ￥5390.00 2-3天	0 货期：2-3天	-	-	-	-

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产品描述：

Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of 5-HT1A receptor, shows a high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50=3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D2 receptor, has moderate affinity (IC50=0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases

靶点：

5-HT1A Receptor:3 nM (IC50);D2 Receptor:0.1-1 μM (IC50);DopamineReceptor; 5-HTReceptor

参考文献：

1. Cervo L, et, al. Potential antidepressant properties of SR 57746A, a novel compound with selectivity and high affinity for 5-HT1A receptors. Eur J Pharmacol. 1994 Feb 21; 253(1-2): 139-47. 2. Simiand J, et, al. Neuropsychopharmacological profile in rodents of SR 57746A, a new, potent 5-HT1A receptor agonist. Fundam Clin Pharmacol. 1993;7(8):413-27. 3. Fournier J, et, al. Protective effects of SR 57746A in central and peripheral models of neurodegenerative disorders in rodents and primates. Neuroscience. 1993 Aug; 55(3): 629-41.

溶解性：

Soluble in DMSO

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.393 ml	11.965 ml	23.929 ml
5 mM	0.479 ml	2.393 ml	4.786 ml
10 mM	0.239 ml	1.196 ml	2.393 ml
50 mM	0.048 ml	0.239 ml	0.479 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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