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10mM in DMSO

Dictamnine

源叶(MedMol)
T88243 一键复制产品信息
484-29-7
C12H9NO2
199.21
Dictamine
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T88243-1ml促销
10mM in DMSO

¥660.00 ¥594.00

5 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. IC50 value: Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) value of 64 microg/ml . Dic induced S phase cell cycle arrest at low concentration and cell apoptosis at high concentration in which loss of mitochondrial membrane potential (Δψmm) was not involved. In addition, inhibition of caspase-3 using the specific inhibitor, z-DQMD-fmk, did not attenuate Dic-induced apoptosis, implying that Dic-induced caspase-3-independent apoptosis.;Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. IC50 value: Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) value of 64 microg/ml . Dic induced S phase cell cycle arrest at low concentration and cell apoptosis at high concentration in which loss of mitochondrial membrane potential (Δψmm) was not involved. In addition, inhibition of caspase-3 using the specific inhibitor, z-DQMD-fmk, did not attenuate Dic-induced apoptosis, implying that Dic-induced caspase-3-independent apoptosis.
体内研究: Dictamine (2 μg/mL,200 μL,每日一次,持续 14 天) 可减轻恶唑酮 诱导的特应性皮炎小鼠模型的皮肤炎症和皮肤肿胀。

Dictamine (50 和 100 mg/kg,口服,每周 3 次) 可抑制 HCT116 异种移植肿瘤模型中的肿瘤生长。

Dictamine (1 和 5 mg/kg,200 μL,涂于皮肤) 可改善 2,4-二硝基氟苯诱导的特应性皮炎小鼠的慢性瘙痒。
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 5.02 ml 25.099 ml 50.198 ml
5 mM 1.004 ml 5.02 ml 10.04 ml
10 mM 0.502 ml 2.51 ml 5.02 ml
50 mM 0.1 ml 0.502 ml 1.004 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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