| 产品描述: | 选择性,ATP竞争性,不可逆的IKKβ抑制剂;Selective, ATP-competitive, irreversible IKKβ inhibitor;SC-514是一种口服有效的,ATP竞争性的IKK-2抑制剂,IC50为3-12 μM,抑制NF-κB依赖性的基因表达,不抑制其他IKK异构体或其他丝-苏氨酸和酪氨酸激酶。;SC-514 is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM, blocks NF-κB-dependent gene expression, does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.A selective and reversible inhibitor of IKKβ (IKK-2) |