5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.;5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.
体内研究:
NLRP3-IN-2 耐受性良好,对体内葡萄糖水平没有影响。 NLRP3-IN-2 (100 mg/kg) 在 AMI 模型中的处理由于缺血+再灌注显著抑制心脏中炎症小体 (caspase-1) 的活性达 90% (P<0.01),并减少梗死面积,病理测量 (>40%,P<0.01) 和肌钙蛋白 I 水平 (>70%,P<0.01)。