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2mM in DMSO

Marbofloxacin

源叶(MedMol)
T88510 一键复制产品信息
115550-35-1
C17H19FN4O4
362.36
Zeniquin;9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic Acid; Marbocyl; Zeniquin
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T88510-1ml促销
2mM in DMSO

¥206.00 ¥185.00

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产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Marbofloxacin is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.;Marbofloxacin is a fluorinated carboxylic acid derivative third generatino quinolone antibacterial.Fluorinated quinolone antibacterial.
体内研究: Administration of Marbofloxacin at 6 mg/kg once daily for 7 days in a Staphylococcus aureus infection in tissue cages in ponies is not effective for the elimination of S. aureus infections from secluded sites . The pharmacokinetic properties of marbofloxacin were investigated in 6 horses after i.v., subcutaneous and oral administration of a single dose of 2 mg/kg bwt and the minimal inhibitory concentrations (MIC) assessed for bacteria isolated from equine infectious pathologies. The clearance of marbofloxacin was mean +/- s.d. 0.25 +/- 0.05 l/kg/h and the terminal half-life 756 +/- 1.99 h. The marbofloxacin absolute bioavailabilities after subcutaneous and oral administration were 98 +/- 11% and 62 +/- 8%, respectively. Considering the breakpoint values of efficacy indices for fluoroquinolones, a marbofloxacin dosage regimen of 2 mg/kg bwt/24 h by i.v., subcutaneous or oral routes was more appropriate for enterobacteriaceae than for S. aureus .
参考文献: 1. Shen J, et al. Marbofloxacin. Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o998-9.
2. Voermans M, et al. Clinical efficacy of intravenous administration of marbofloxacin in a Staphylococcus aureus infection in tissue cages in ponies. J Vet Pharmacol Ther. 2006 Dec;29(6):555-60.
3. Bousquet-Melou A, et al. Pharmacokinetics of marbofloxacin in horses. Equine Vet J. 2002 Jul;34(4):366-72.
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.76 ml 13.798 ml 27.597 ml
5 mM 0.552 ml 2.76 ml 5.519 ml
10 mM 0.276 ml 1.38 ml 2.76 ml
50 mM 0.055 ml 0.276 ml 0.552 ml
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参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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