| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T88582-1ml促销 |
2mM in DMSO | ￥206.00 ￥186.00 |
>10 | - | - | - | - |
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| 产品描述： | TNF-α 选择性抑制剂 | 活化剂 | 拮抗剂;TNF-α Selective Inhibitors | Activators | Antagonists;;InformationDemethyleneberberine (DMB), a component of Cortex Phellodendri Chinensis (CPC), significantly alleviates the weight loss and diminishesmyeloperoxidase (MPO)activity, while significantly reduces the production of pro-inflammatory cytokines, such asinterleukin (IL)-6andtumor necrosis factor-α (TNF-α), and inhibits the activation ofNF-κBsignaling pathway. Demethyleneberberine (DMB) potentially ameliorates NAFLD (Non-alcoholic fatty liver disease) by activatingTargetsNF-κB ; MPO ; IL-6 ; TNF-α ; IL-1β 33791, | ||||||||||||||||||||
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| 参考文献： | 1. Zhang P, et al. Demethyleneberberine, a natural mitochondria-targeted antioxidant, inhibits mitochondrial dysfunction, oxidative stress, and steatosis in alcoholic liver disease mouse model. J Pharmacol Exp Ther. 2015 Jan;352(1):139-47. 2. Chen YY, et al. Demethyleneberberine alleviates inflammatory bowel disease in mice through regulating NF-κB signaling and T-helper cell homeostasis. Inflamm Res. 2017 Feb;66(2):187-196. 3. Qiang X, et al. Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress. Biochem Biophys Res Commun. 2016 Apr 15;472(4):603-9. |
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| 保存条件： | -80℃（运输条件：冰袋低温运输） | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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