选择性Bax活化剂;诱导Bax介导的细胞凋亡;Selective Bax activator; induces Bax-mediated apoptosis;BAM7是一种直接的,选择性的促凋亡Bax激动剂,EC50为3.3 μM;BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM
参考文献:
1. Gavathiotis E, et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012 Jul;8(7):639-45.