SG-094 (90 nmol/kg; every 2-3 days over a 10-day timescale) 抑制小鼠的肝细胞癌 (HCC) 肿瘤生长。
参考文献:
1. Müller M, et, al. Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth. Cell Chem Biol. 2021 Aug 19;28(8):1119-1131.e27.