货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
T90358-1ml促销	10mM in DMSO	￥100.00 ￥90.00 T90358-1ml ￥90.00 现货	5 5	-	-	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

T90358-1ml促销

10mM in DMSO

￥100.00 ￥90.00

产品描述：

铅螯合剂和ROS°清除剂;Lead chelating agent and ROS° scavenger;DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents.;DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents.A water-soluble chelating agent.

体内研究：

Succimer 可以降低铅暴露动物的红细胞中葡萄糖?6-磷酸脱氢酶?(G6PD)?活性。

参考文献：

1. Gürer H, et al. Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats. Toxicology. 1998 Jul 17;128(3):181-9.
2. Beaudin SA, et al. Succimer chelation normalizes reactivity to reward omission and errors in lead-exposed rats. Neurotoxicol Teratol. 2007 Mar-Apr;29(2):188-202.

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	5.488 ml	27.439 ml	54.879 ml
5 mM	1.098 ml	5.488 ml	10.976 ml
10 mM	0.549 ml	2.744 ml	5.488 ml
50 mM	0.11 ml	0.549 ml	1.098 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(1篇)

1. [IF=3.7] Baodong Hu et al."Efficient Biosynthesis of Furanocoumarin Intermediate Marmesin by Engineered Escherichia coli."ACS Synthetic Biology.2025;XXXX(XXX):XXX-XXX

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

内消旋-2,3-二巯基丁二酸

meso-2,3-Dimercaptosuccinic acid

参考文献(1篇)

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)