DMBA被p450酶氧化产生的代谢物能和DNA共价形成加合物,形成脱嘌呤碱基位点。 常用于在动物身上诱导皮肤和乳房瘤,也能诱发白血病和其它瘤。7,12-Dimethylbenz[a]anthracene is a polycyclic aromatic hydrocarbon. It is used in cancer research. It is a carcinogenic organic pollutant generated from the incomplete combustion of gasoline and coal.;7,12-Dimethylbenz[a]anthracene has been used to induce skin cancer in mice, buccal pouch carcinogenesis in syrian golden hamsters and breast cancer in rats.7,12-Dimethylbenz[a]anthracene is a polycyclic aromatic hydrocarbon. It is used in cancer research. It is a carcinogenic organic pollutant generated from the incomplete combustion of gasoline and coal.