| 产品描述: | DL-Menthol triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. The (-)-Menthol form exists naturally in nature, primarily found in fruit extracts or spearmint extracts. This racemic mixture could theoretically be created by the hydrogenation of the monoterpene pulegone.;DL-Menthol triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. The (-)-Menthol form exists naturally in nature, primarily found in fruit extracts or spearmint extracts. This racemic mixture could theoretically be created by the hydrogenation of the monoterpene pulegone.A chemical which triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. |
| 体内研究: |
DL-Menthol (0.2-3.0 mM;水体给药;单次;短期处理) 在日本青鳉 (Oryzias latipes)、金鱼 (Carassius auratus) 和斑马鱼 (Danio rerio) 模型中,呈剂量依赖性诱导手术麻醉,高浓度时 (3.0 mM) 先引发快速运动,然后转为麻醉。0.5 mM DL-Menthol 在日本青鳉、金鱼和斑马鱼中造成的手术麻醉百分率分别为 100%,90% 和 100% of zebrafish。 |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
6.399 ml |
31.996 ml |
63.992 ml |
| 5 mM |
1.28 ml |
6.399 ml |
12.798 ml |
| 10 mM |
0.64 ml |
3.2 ml |
6.399 ml |
| 50 mM |
0.128 ml |
0.64 ml |
1.28 ml |
|
| 注意: |
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