| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
T90556-1ml促销 |
10mM in DMSO | ￥176.00 ￥158.00 |
10 | - | - | - | - |
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| 产品描述： | 可逆钠离子流入抑制剂。长效酰胺局麻药。;Reversible sodium ion influx inhibitor. Long-acting amide local anaesthetic agent.;Ropivacaine hydrochloride monohydrate 能阻断神经纤维的冲动传导，能可逆的抑制钠离子流。;Ropivacaine hydrochloride monohydrate is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.A reversible blockade of impulse propagation | ||||||||||||||||||||
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| 靶点： | IC50: sodium ion influx;IC50: 402.7 μM (TREK-1 in COS-7 cell's membrane) | ||||||||||||||||||||
| 体内研究： | Epidural administration of Ropivacaine hydrochloride monohydrate effectively blocks neuropathic pain (both mechanical allodynia and heat hyperalgesia) without induction of analgesic tolerance and significantly delays the development of neuropathic pain produced by peripheral nerve injury. Ropivacaine hydrochloride monohydrate inhibits pressure-induced increases in filtration coefficient (Kf) without affecting pulmonary artery pressure (Ppa), pulmonary capillary pressures (Ppc), and zonal characteristics (ZC). Ropivacaine hydrochloride monohydrate prevents pressure-induced lung edema and associated hyperpermeability as evidence by maintaining PaO2, lung wet-to-dry ratio and plasma volume in levels similar to sham rats. Ropivacaine hydrochloride monohydrate inhibits pressure-induced NO production as evidenced by decreased lung nitro-tyrosine content when compared to hypertensive lungs. |
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| 保存条件： | -80℃（运输条件：冰袋低温运输） | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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