| 产品描述: | 维生素B6代谢产物。;Vitamin B6 metabolite.;Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine.;Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine.A vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. |
| 靶点: |
IC50: active form of vitamin B6 |
| 体内研究: |
Pyridoxal 5'-phosphate monohydrate (1 mg/kg, ip, single dose) 可在小鼠模型中减轻 Aβ25-35 引起的空间记忆障碍和长期记忆障碍。 Pyridoxal 5'-phosphate monohydrate (600 mg/kg/day, po for 16 weeks) 可抑制晚期糖基化终产物 (AGE) 的形成,并阻止 Streptozotocin 诱发的大鼠糖尿病肾病的发展。 |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.771 ml |
18.857 ml |
37.713 ml |
| 5 mM |
0.754 ml |
3.771 ml |
7.543 ml |
| 10 mM |
0.377 ml |
1.886 ml |
3.771 ml |
| 50 mM |
0.075 ml |
0.377 ml |
0.754 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |