| 产品描述: | 选择性H 2拮抗剂;Selective H 2 antagonist;Nizatidine是一种组胺H2受体拮抗剂,作用于AChE,IC50为6.7 nM。;Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.An inhibitor of gastric acid secretion. |
| 体内研究: |
Nizatidine (oral gavage; 27 mg/kg; once daily; at 12 weeks of age and were sacrificed at 30 weeks after development of HCC in the setting of nonalcoholic steatohepatitis (NASH)) results in a 35% reduction of tumor nodules relative to controls. Nizatidine results in a 60% reduction in tumor nodules, reduces collagen proportional area and expression of profibrotic markers in DEN-injured rats. Nizatidine (oral gavage; 27 mg/kg; once daily; 4 weeks) decreases the incidence of gastric ulceration, and significantly decreases the mean ulcer score and ulcer index in male albino rats. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.017 ml |
15.085 ml |
30.17 ml |
| 5 mM |
0.603 ml |
3.017 ml |
6.034 ml |
| 10 mM |
0.302 ml |
1.508 ml |
3.017 ml |
| 50 mM |
0.06 ml |
0.302 ml |
0.603 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |