首页
订购/客服:400-666-5481

巴卡丁 III

    
10mM in DMSO

Baccatin III

源叶(MedMol)
T91365 一键复制产品信息
27548-93-2
C31H38O11
586.63
巴卡丁三;O-De[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]paclitaxel
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T91365-1ml促销
10mM in DMSO

¥612.00 ¥550.00

5 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro;Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitroAn apoptosis inducer and precursor to paclitaxel/taxol
体内研究: Baccatin III (0.05-0.5 mg/kg;灌胃;每日一次;17-19 天) 显著抑制 BALB/c 小鼠 4T1 乳腺癌或 CT26 结肠癌的肿瘤生长并减少髓源性抑制细胞 (MDSC) 的积累。
Baccatin III (5-10 mg/kg;腹腔注射;单次;21 天) 通过抑制 TGF-β1 减轻 C57BL/6 小鼠中 Bleomycin 诱导的肺纤维化。
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.705 ml 8.523 ml 17.047 ml
5 mM 0.341 ml 1.705 ml 3.409 ml
10 mM 0.17 ml 0.852 ml 1.705 ml
50 mM 0.034 ml 0.17 ml 0.341 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×