| 产品描述: | 2,2'-Dipyridyl is a metalloprotease inhibitor that is also a high-affinity chelator of iron. It may inhibit Fe2+ containing enzymes at 10-8 M. |
| 体内研究: |
2,2'-Bipyridine (40 mg/kg;sc;一次) 产生初始高血糖 (2 小时增加 53.8 mg/100 mL),然后在 24 小时出现短暂的低血糖阶段,不会产生永久性糖尿病。 |
| 参考文献: |
1. Chen D, et al. Discovery of caerulomycin/collismycin-type 2,2'-bipyridine natural products in the genomic era. J Ind Microbiol Biotechnol. 2019;46(3-4):459-468. 2. Kenny A D, et al. The hyperglycemic activity of 2, 2'-bipyridine[J]. Journal of Pharmacology and Experimental Therapeutics, 1962, 135(3): 317-322. |
| 保存条件: |
-80℃,干燥(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
6.402 ml |
32.012 ml |
64.025 ml |
| 5 mM |
1.28 ml |
6.402 ml |
12.805 ml |
| 10 mM |
0.64 ml |
3.201 ml |
6.402 ml |
| 50 mM |
0.128 ml |
0.64 ml |
1.28 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |