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1H-[1,2,4]恶二唑并[4,3-a]喹喔啉-1-酮

    
10mM in DMSO

1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one

源叶(MedMol)
T91551 一键复制产品信息
41443-28-1
C9H5N3O2
187.16
ODQ;ODQ
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T91551-1ml促销
10mM in DMSO

¥720.00 ¥648.00

5 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: 选择性,有效的NO敏感鸟苷酸环化酶抑制剂;Selective, potent inhibitor of NO-sensitive guanylyl cyclase;ODQ is a selective and potent GCS (soluble guanylyl cyclase, sGC) inhibitor that binds competitively with nitric oxide. The GCS (sGC) serves as a receptor for nitric oxide, which is involved in the production of cyclic guanosine monophosphate (cGMP). In prostate cancer cell studies, ODQ induced caspase-3, enhanced cell death, and blocked cell migration. Inhibition of GCS (sGC) through ODQ results in blocking the actions of nitric oxide on vascular and platelet smooth muscle.;ODQ is a selective and potent GCS (soluble guanylyl cyclase, sGC) inhibitor that binds competitively with nitric oxide. The GCS (sGC) serves as a receptor for nitric oxide, which is involved in the production of cyclic guanosine monophosphate (cGMP). In prostate cancer cell studies, ODQ induced caspase-3, enhanced cell death, and blocked cell migration. Inhibition of GCS (sGC) through ODQ results in blocking the actions of nitric oxide on vascular and platelet smooth muscle.A selective and potent sGC (soluble guanylyl cyclase) inhibitor.
体内研究: ODQ (2 mg/kg;ip) 减少麻醉大鼠体内由革兰氏阳性或革兰氏阴性菌壁碎片引起的多器官损伤和功能障碍。
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 5.343 ml 26.715 ml 53.43 ml
5 mM 1.069 ml 5.343 ml 10.686 ml
10 mM 0.534 ml 2.672 ml 5.343 ml
50 mM 0.107 ml 0.534 ml 1.069 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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