一般描述:膦酰基乙酸可在病毒感染的人成纤维细胞中抑制特异性的人巨细胞病毒DNA合成。它还能够抑制感染细胞中单纯疱疹病毒DNA的合成以及在体外病毒特异性DNA聚合酶的活性。应用:膦酰基乙酸已被用作病毒DNA复制的一种抑制剂,以研究受感染的低传代牛细胞中感染细胞蛋白0(bICP0)的定位。它还可以磷酸盐非依赖性方式用作微生物生长的一种磷源。;General description:Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro. application:Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.