| 产品描述: | D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.It can be used as a chiral starting material to synthesize:• An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.• (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.• A bicyclic diterpene named isofregenedadio;D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.It can be used as a chiral starting material to synthesize:• An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.• (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.• A bicyclic diterpene named isofregenedadio |
| 参考文献: |
1. Hajare AK, et al. Synthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-pantolactone. J Org Chem. 2011 Feb 4;76(3):963-6. 2. Konno T, et al. D-pantolactone as a circular dichromism (CD) calibration. Anal Biochem. 1975 Jul;67(1):226-32. 3. Fang H, et al. Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors. Bioorg Med Chem. 2019 Oct 15;27(20):115069. |