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Baloxavir marboxil

    
10mM in DMSO

Baloxavir marboxil

源叶(MedMol)
T92398 一键复制产品信息
1985606-14-1
C27H23F2N3O7S
571.55
Carbonic acid,[[(12aR)​-​12-​[(11S)​-​7,​8-​difluoro-​6,​11-​dihydrodibenzo[b,​e]​thiepin-​11-​yl]​-​3,​4,​6,​8,​12,​12a-​hexahydro-​6,​8-​dioxo-​1H-​[1,​4]​oxazino[3,​4-​c]​pyrido[2,​1-​f]​[1,​2,​4]​triazin-​7-​yl]​oxy]​methyl methyl ester
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T92398-1ml促销
10mM in DMSO

¥206.00 ¥185.00

6 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: 抗病毒抑制剂;Antiviral Inhibitors;;InformationBaloxavir marboxil Baloxavir marboxil, a cap-endonuclease inhibitor, is an antiviral drug.In vivoSingle-dose oral baloxavir marboxil is well tolerated, had a favorable safety profile, and has favorable pharmacokinetic characteristics, including a long half-life, supporting single oral dosing. In nonclinical studies, baloxavir marboxil is a prodrug and is converted to an active form, baloxavir acid, by hydrolysis. After single oral administration in rats and monkeys, plasma concentrations of baloxavir marboxil are below the lower limit of quantification (LLOQ) at all sampling points, and area under the plasma concentration-time curve of baloxavir acid increased dose proportionally. The major excretion route of radioactivity is via fecal excretion, whereas urinary excretion was low in rats and monkeys. Baloxavir marboxil has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains resistant to current antiviral agents. In murine models of seasonal influenza and avian influenza A(H5N1) or A(H7N9), orally administered baloxavir is associated with rapid reductions in pulmonary viral loads and decreased mortality.
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.75 ml 8.748 ml 17.496 ml
5 mM 0.35 ml 1.75 ml 3.499 ml
10 mM 0.175 ml 0.875 ml 1.75 ml
50 mM 0.035 ml 0.175 ml 0.35 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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