| 产品描述: | Fluorometholone Acetate 是一种合成的皮质类固醇, 用于治疗类固醇反应性眼睛炎症。 |
| 靶点: |
IC50: 2.18 μM (human carbonic anhydrase (hCA)-I) and 17.5 μM (hCA-II);Ki: 1.044 μM (hCA-I) and 9.98 μM (hCA-II) |
| 体内研究: |
Hourly topical administration of 0.1% Fluorometholone acetate ophthalmic suspension produced, on the average, a 47% reduction in the polymorphonuclear leukocytes invading the cornea during an experimentally induced inflammatory keratitis in New Zealand albino rabbits (1.5-2.0 kg). Fluorometholone acetate (0.1%) formulated as a high-viscosity carbomer gel and applied at three-hour intervals reduced invading leukocytes in the cornea an average of 48%, an effect not significantly different from hourly administration of the suspension. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.389 ml |
11.947 ml |
23.895 ml |
| 5 mM |
0.478 ml |
2.389 ml |
4.779 ml |
| 10 mM |
0.239 ml |
1.195 ml |
2.389 ml |
| 50 mM |
0.048 ml |
0.239 ml |
0.478 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |