| 产品描述: | 促智剂,奥拉西坦研究显示具有学习和记忆的改善和认知功能障碍的预防。作用机制还没有被量化,但目前的理论认为谷氨酸和胆碱神经传递的调控与PKC介入的可能性。;Nootropic agent shown to exhibit learning and memory improvement and cognitive function impairment prevention. Mechanism of action has not been quantified, but current theories suggest a modulation of glutamatergic and cholinergic neurotransmissions with the possibility of PKC involvement. |
| 体内研究: |
Oxiracetam (30 mg/kg;腹腔注射;4 周) 可在大鼠中改善慢性脑缺血引起的认知障碍。 |
| 参考文献: |
1. Zhang H, et al. Oxiracetam Offers Neuroprotection by Reducing Amyloid β-Induced Microglial Activation and Inflammation in Alzheimer's Disease. Front Neurol. 2020 Jul 17;11:623 2. Yao XL, et al. Oxiracetam can improve cognitive impairment after chronic cerebral hypoperfusion in rats. Psychiatry Res. 2016 Dec 30;246:284-292. 3. Li W, et al. (S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Sci Rep. 2017 Aug 30;7(1):10052. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
6.323 ml |
31.614 ml |
63.227 ml |
| 5 mM |
1.265 ml |
6.323 ml |
12.645 ml |
| 10 mM |
0.632 ml |
3.161 ml |
6.323 ml |
| 50 mM |
0.126 ml |
0.632 ml |
1.265 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |