货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
T93073-1ml促销	10mM in DMSO	￥900.00 ￥710.00 T93073-1ml ￥710.00 现货	7 7	-	-	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

T93073-1ml促销

10mM in DMSO

￥900.00 ￥710.00

产品描述：

钙通道抑制剂;Calcium Channel Inhibitors;;InformationEfonidipine Efonidipine (NZ-105) is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.TargetsT-type calcium channelIn vitroAlthough efonidipine is not a specific T-type calcium channe (TTCC) blocker as it could also block L-type calcium channe (LTCC), its efficacy in blocking TTCC is much greater than that of LTCC. Efonidipine exerts an inhibitory effect on aldosterone synthesis and secretion in a human adrenocortical cell line (H295R), an effect that is mediated, at least in part, by suppression of 11-β-hydroxylase and aldosterone synthase expression. Efonidipine also suppresses both Ang II- and K+-induced aldosterone secretion, but it blocks the latter at much lower concentrations than the former.In vivoEfonidipine could provide broader beneficial effects including the heart, liver, and plasma, and antioxidant in iron-overload condition in both WT(muβ+⁄+) and HT(muβth-3 ⁄+,) mice.Cell Research(from reference)Cell lines：The NCI-H295R human adrenocortical cell line (H295) Concentrations：0.3 μM and 3 μM Incubation Time：24 h

保存条件：

-80℃（运输条件：冰袋低温运输）

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.583 ml	7.916 ml	15.831 ml
5 mM	0.317 ml	1.583 ml	3.166 ml
10 mM	0.158 ml	0.792 ml	1.583 ml
50 mM	0.032 ml	0.158 ml	0.317 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

伊福地平

Efonidipine

参考文献

质检证书(COA)

如何获取质检证书(COA)?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)