角鲨烯是一种脂质不皂化物,最初是从鲨鱼的肝油中发现的,1914年被命名为Squalene,属开链三萜,又称鱼肝油萜。油状液体。微有令人愉快的气体。对光敏感。吸收氧变成黏性如亚麻油状。易溶于乙醚、石油醚、丙酮、四氯化碳和其他油脂溶剂,微溶于乙醇和冰乙酸,几乎不溶于水。有刺激性。;Squalene is a biosynthetic precursor for all steroids that is cytoprotective to normal cells exposed to carcinogens and antitumor agentsBiosynthetic precursor to all steroids. Cytoprotective to normal cells exposed to carcinogens and antitumor agents
1. Muzalevskaya EN, et al. SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES. Eksp Klin Farmakol. 2015;78(6):30-6. 2. Fernando Warleta, et al. Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA-MB-231 human breast cancer cells. Food Chem Toxicol. 2010 Apr;48(4):1092-100. 3. Clara Gabás-Rivera, et al. Dietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice. PLoS One. 2014 Aug 12;9(8):e104224.