强效选择性乙肝病毒抑制剂;Potent and selective hepatitis B virus inhibitor;;
靶点:
EC50: 3.75 nM (anti-HBV, HepG2 cell)
体内研究:
Daily oral treatment with BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduces the level of woodchuck hepatitis virus (WHV) viremia in chronically infected woodchucks.