| 体内研究: |
CCl4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl4-induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed. |
| 参考文献: |
1. O Shimada, et al. Hydroxyl radical scavenging action of tinoridine. Agents Actions. 1986 Nov;19(3-4):208-14.2. Yasuda H, et al. The protective effect of tinoridine against carbon tetrachloride hepatotoxicity. Toxicol Appl Pharmacol. 1980 Mar 15;52(3):407-13. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.834 ml |
14.169 ml |
28.338 ml |
| 5 mM |
0.567 ml |
2.834 ml |
5.668 ml |
| 10 mM |
0.283 ml |
1.417 ml |
2.834 ml |
| 50 mM |
0.057 ml |
0.283 ml |
0.567 ml |
|
| 注意: |
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