| 产品描述： | Bufalin is a C-24 steroid with an α-pyrone ring positioned at C-17. It is present in the venom glands and skin of toad, Venenum Bufonis.Bufalin is a cardiotonic steroid[5] and is digoxin-like component of Chan Su.Bufalin has been used:• to test its effect on invasion and activation of nuclear factor kappa- B (NF-κB) cells and tumor necrosis factor-α (TNF-α) stimulated rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs)• as a nuclear receptor coactivator 3 (NCOA3) inhibitor in chondrocytes• to test its anti-metastasis effect in lung cancer cells (NCI-H460) resistant to gefitinib |
| 靶点： |
Kd: 42.5 nM (Na,K-ATPase α1), 45 nM (Na,K-ATPase α2), 40 nM (Na,K-ATPase α3) |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.587 ml |
12.936 ml |
25.872 ml |
| 5 mM |
0.517 ml |
2.587 ml |
5.174 ml |
| 10 mM |
0.259 ml |
1.294 ml |
2.587 ml |
| 50 mM |
0.052 ml |
0.259 ml |
0.517 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京